Angiogenesis and the prevention of alveolar osteitis: a review study
Saghiri Mohammad Ali, Asatourian Armen, Sheibani Nader,
소속 상세정보
( Saghiri Mohammad Ali ) - University of Wisconsin School of Medicine and Public Health Department of Ophthalmology and Visual Sciences
( Asatourian Armen ) - Dr. H. Afsar Lajevardi Research Cluster Angiogenesis Regenerative Medicine Sector
( Sheibani Nader ) - University of Wisconsin School of Medicine and Public Health Department of Ophthalmology and Visual Sciences
Abstract
Angiogenesis is one of the essential processes that occur during wound healing. It is responsible for providing immunity as well as the regenerative cells, nutrition, and oxygen needed for the healing of the alveolar socket following tooth extraction. The inappropriate removal of formed blood clots causes the undesirable phenomenon of alveolar osteitis (AO) or dry socket. In this review, we aimed to investigate whether enhanced angiogenesis contributes to a more effective prevention of AO. The potential pro- or anti-angiogenic activity of different materials used for the treatment of AO were evaluated. An electronic search was performed in the PubMed, MEDLINE, and EMBASE databases via OVID from January 2000 to September 2016 using the keywords mentioned in the PubMed and MeSH (Medical Subject Headings) terms regarding the role of angiogenesis in the prevention of AO. Our initial search identified 408 articles using the keywords indicated above, with 38 of them meeting the inclusion criteria set for this review. Due to the undeniable role of angiogenesis in the socket healing process, it is beneficial if strategies for preventing AO are directed toward more proangiogenic materials and modalities.
키워드
Dry socket; Endothelial cells; Regeneration
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